H4CBD research

H4CBD, an improved version of CBD?

H4CBD or HHCBD , like other synthetic compounds derived from CBD such as H2CBD , were first synthesized in 1940 by the Todd group through catalytic hydrogenation of CBD, in other words, the addition of hydrogen atoms to the CBD molecule. However, it's important to know that this compound goes by other names like CyclohexylCBD or HHCBD , and you'll often see it referred to simply as "hydrogenated CBD." You have to be careful with this last nomenclature since other hydrogenated CBD compounds such as H2CBD or 8,9-Dihydrocannabidiol often receive this same name, which can create some confusion.

Decades later, in 2006, a group of researchers led by Shimon Ben-Shabat discovered that H4CBD has a special affinity with the CB1 cannabinoid receptor in our body, with anti-inflammatory properties that act independently of the action of this cannabinoid receptor.

Broadly speaking, and thanks to the fact that this affinity with the CB1 receptor is even greater than in the case of CBD, we would be talking about an "improved" version, more powerful, of CBD or cannabidiol, probably the most widely used cannabinoid in the medical field. Thus, H4CBD presents clear anti-inflammatory, analgesic, anxiolytic, and neuroprotective effects , although more research on this compound and its relationship with our endocannabinoid system is undoubtedly needed - as well as clinical trials with humans - to confirm these properties, already known by researchers and CBD users.


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